Consequently, liposome having phytomedicines with antimicrobial activity can be a better solution to treat various infectious diseases. The encapsulation of a flavonoid extracted from Erigeron breviscapus Vant. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780128152720000131, URL: https://www.sciencedirect.com/science/article/pii/B978185573463050014X, URL: https://www.sciencedirect.com/science/article/pii/B9780123849373000148, URL: https://www.sciencedirect.com/science/article/pii/B9780128164839000086, URL: https://www.sciencedirect.com/science/article/pii/B9780128146194000240, URL: https://www.sciencedirect.com/science/article/pii/S1043452619300245, URL: https://www.sciencedirect.com/science/article/pii/S0963996913003487, Climate Change and Agricultural Ecosystems, 2019, Plants Infused Water as Preferred Healthy Drinks, Sources of natural antioxidants: vegetables, fruits, herbs, spices and teas, ProfessorN.V. The composition of essential oils seems to change with changing temperatures; for instance, a 60% p-Cymene content was found during winter, while a 42% carvacrol content was found during summer time (Lianopoulou and Bosabalidis, 2014). Shi-Biao Wu, ... Edward J. Kennelly, in Food Research International, 2013. Origanum dictamnus (dittany of Crete): testam ents, uses, and trade of a . A fine example of this is as follows: as much as five families that were prior included in Umbelliferae (Apiaceae) now have to be reclassified due to the fact that they produce iridoid compounds which makes them closer to Dipsacales (Bhargava et al., 2013). 23.1). Dry oregano as well as extracts obtained by using solvents of different polarity (hexane, dichlormethane, methanol) have been tested as retarders of lipid oxidation in model systems or in real food products.77,79,97,184 Abdalla and Roozen150 reported that oregano acetone extract was more active in sunflower oil than in its 20% oil-in-water emulsion during oxidation in the dark at 60 °C. A large intracellular space for accumulating air at high temperatures was found in mesophyll cells (Lianopoulou and Bosabalidis, 2014). Aromatic and strangely beautiful, Origanum dictamnus (Dittany of Crete) is a bushy sub-shrub forming a spreading mound of small, rounded, fuzzy silvery-white leaves. Not sure which Origanum - Oregano to pick? Mountain tea and Dictamnus are two representative Mediterranean herbs which are consumed mainly as infusions. In contact with the hydrophobic solvent, these lipids self-assembled into a globular vesicular structure. In view of the differences between the extraction techniques, it is obvious that extracts from the same plant material may widely vary with respect to their antioxidant content and pattern. This objective has mainly been approached by measuring the increase of the antioxidant capacity in plasma and tissue following an oral intake of a plant food or herb infusion (Henning et al., 2005). It is one of the most studied phytomedicines because of its excellent biological activities (Zorofchian Moghadamtousi et al., 2014). Depsides were not previously reported in the Myrtaceae family until 2006. Application of liposomal curcumin downregulates proliferation and induces apoptosis by inhibiting the nuclear transcription factor (NF-κB) pathway in cancerous pancreatic cells (Li et al., 2005). HPLC is the preferred way of providing standardized information about the concentration of individual antioxidants in plant extracts. Latin name: Origanum dictamnus Synonyms: Amaracus dictamnus Family: Labiatae Medicinal use of Dittany Of Crete: The flowering plant has been used as an antirheumatic, oxytocic, stomachic and vulnerary, though these uses … harvested in India (Joshi, Melkani, Nailwal, Prasad, & Bisht, 2018). Pungent, Bitter. Origanum onites, Satureja thymbra, Coridothymus capitatus, Origanum dictamnus were also investigated.185–187, The water-soluble fraction of the methanol extract of oregano leaves was purified with polyamide chromatography to give five polar compounds188,189–rosmarinic acid, caffeic acid, protocatechuic acid 61, a new glucoside of protocatechuic acid 62, and a derivative of rosmarinic acid, 2-caffeoyloxy- 3-[2-(4-hydroxybenzyl)-4,5-dihydroxy]phenylpropionic acid 63. Uses: 1. According to Pereira et al. Recent studies show possible bioactivity of the aromatic plant Pelargonium purpureum aqueous infusion after five days administration in mice (Koutelidakis et al., 2009, 2010). Only plants will be removed from the collection. (2018), this acyclic monoterpene is identified in as much as 200 plant species, but in different amounts depending on the analyzed part of the plant, its harvest time and geographic/climatic conditions. Antibiotic drug resistance is a great threat for the treatment of several pathogenic microorganisms. In fact to tolerance cold stress, plants change their survival strategies by redistributing resources and lowering growth (Eremina et al., 2016). Further, curcumin induces tumor suppressor pathway (p53) and ultimately leads to the death of cancer cells. Acyclic monoterpenes are derivatives of 2,6 dimethyloctane, and most commonly identified in plant sources are: geraniol, linalool, ocimene, myrcene, aloocimene, nerol, citronellol, etc. Selection of a suitable extraction procedure can increase the concentration of antioxidants. So far, monoterpenes have been identified in plants: leaves, fruits, roots, seeds and barks; identified compounds may be somewhat different depending on the part of the plant from which they are isolated (Talapatra & Talapatra, 2015). In the hexane extract α-, β-, γ- and δ-tocopherols were found.186. This plant has a long history as culinary and medicinal herb and is mentioned in Greek mythology. illeg. Note this is the default cart. Origanum dictamnus is a perennial plant that can grow up to 0.20 metres tall. However, the antioxidant pattern is usually rather complex, thus making the prediction of a mixture’s potency based on compositional data difficult. QE is also mainly found in mountain tea and inhibits tumor growth by reducing expression of Ras protein, the protein that involved in cell growth, differentiation, and survival. It is hardy to zone (UK) 7. Herbal infusions have also been reported to possess chemopreventive effect. Other species of oregano and its close relatives, e.g. Further, on their size, ULVs can be classified into small, intermediate, and large ULVs (Vemuri and Rhodes, 1995). To inhibit its toxic effects, eugenol was successfully encapsulated into the lipid vesicles and can be produced on a large scale (Sebaaly et al., 2016, 2015). Origanum dictamnus. However, the majority of these oils are insoluble in water and susceptible to oxidation as well as unstable at high temperature. Proestos Charalampos, ... Maria Kapsokefalou, in Tea in Health and Disease Prevention, 2013. Interest in employing antioxidants from natural sources to increase the shelf life of foods is considerably enhanced by consumer preference for natural ingredients and concerns about the toxic effects of synthetic antioxidants. According to Khan et al. Celastrol possesses a potent anticancer activity, but due to insolubility issue, its use is limited. Sweet marjoram is widely used as a flavouring for salad dressings, vegetables, legumes and oils[7, 14, 27, 61, 171, 238]. Not sure which Origanum - Oregano to pick?Compare All Origanum - Oregano, Buy Origanum dictamnus (Dittany of Crete), Great Plant Combination Ideas with Origanum - Oregano. Antitumor effect found in herbal infusions was suggested to be attributed by the presence of phenolic content and other phytochemicals. Based on the interaction between drug and lipid, several methods are developed for the synthesis of liposomes. Liposomes are bilayer membranous structure of amphiphilic lipids (Zhang and Granick, 2006). The liposomal PTX formulation was also effective against lung cancer (Zhao et al., 2011). Most of us are familiar with parsley, sage, rosemary and thyme, but what is dittany of Crete?Read on to learn more. PTX inhibits proliferation of the cancer cells by interfering in microtubule system of the cell cycle at late G2 or M phase. Dittany of Crete (Origanum dictamnus… It is in flower from June to August. They have multiple roles, including protective against herbivores which was demonstrated after analyses of the plant parts damaged by their predators—often insects. It has a very potent antimicrobial activity (Marchese et al., 2017). Liposomal formulations have been constructed to increase the solubility as well as the stability of these oils (Detoni et al., 2012; Gortzi et al., 2006). For example, cinnamic acid (29) and O-coumaric acid (30), as well as protocatechuic acid (31) and methyl protocatechuic acid (32) were identified (Reynertson et al., 2006); syringin-3-O-glucoside (27) and syringin (28) were determined and reported from fresh jaboticaba MeOH extract more recently (Wu et al., 2012). Low temperatures directly affect the physiology of plants (Ruelland et al., 2009). Curcumin successfully showed its bioactivities during in vitro studies. Furthermore, cationic liposomes constructed using charged lipid molecule to increase the delivery of drugs to negatively charged target cells. Curcumin liposomes significantly inhibited the growth of glioma cells. Figure 23.1. Dictamnus (Origanum dictamnus), is an aromatic plant found in Crete. When Withania somnifera (ashwagandha), also known as Indian ginseng, is exposed to low temperatures it shows increased accumulation of withanolides in its leaves (Khan et al., 2015; Kumar et al., 2012). Test systems that evaluate the radical scavenging ability of antioxidants aim to simulate the basic mechanisms involved in lipid oxidation by measuring either the reduction of stable radicals or radicals generated by radiolysis, photolysis, or the Fenton reaction (Blois, 1958; Madsen et al., 1996). Currently, liposomes are the most widely studied and clinically approved lipid-based vesicle systems for the delivery of antimicrobial drugs. Oregano (Origanum vulgare L.) is very often used in Greek cuisine as seasoning due to its strong flavor. Medicinal importance of genus Origanum: A review Shayista Chishti1*, Zahoor A. Kaloo1 and Phalestine Sultan2 1Department of Botany, University of Kashmir, Hazratbal, Srinagar, ... Vogel, Origanum dictamnus L., Origanum saccatum Davis, Origanum solymicum Davis and Origanum … Pelargonio (Pelargonium purpureum) is a plant of local interest, which is used as additive in cakes (Figure 14.1). Jovana PetrovićDejan StojkovićMarina Soković, in Advances in Food and Nutrition Research, 2019. (2011) showed membrane damage among 11 varieties of fennel species, and explained that adaptation to different environmental stresses is dependent on plant species. Bicyclic group of monoterpenes include: camphor, thujone, caren, sabinene, umbellulol, pinene, thujone, among others (Talapatra & Talapatra, 2015). These constructs called phytosomes. 4, originally found in lichens, are a unique kind of phenolic compound composed of some monocyclic aromatic groups linked by the ester bonds. The dispersion of metabolites in different organs is also affected by cold stress and is important for the internal balance and survival of plants. Dittany of Crete herb is the common name for the flowering above-ground (aerial) parts of Origanum dictamnus L. The plant is cultivated or gathered to obtain the above-ground parts for medicinal use. Indication 2) Traditional herbal medicinal product used for the relief of mild gastrointestinal disorders. Limonene is a terpene hydrocarbon widely spread among citrus essential oils, very appealing for perfumes industry (Kim et al., 2013). Phytosome-bearing curcumin showed better antiaging activity when compared with another lipid-based vesicular system (Gupta and Dixit, 2011). According to Fahn and Cutler (1992), plants which grow in cold atmospheres possess some special features, like dense glandular and nonglandular hairs, thick, curled and small leaves, increased number of stomata, high content of phenol in epidermis and mesophyllic cells, numerous sclerenchymatic fibers, and compact mesophyll with developed palisade parenchyma. The antioxidant reactions involve multiple steps including the initiation, propagation, branching, and termination of free radicals. It is endemic on Dicti Mountains on Crete, some believe dicti = dictamnus (tamnus or thamnos = small bush). PEGylated liposome significantly increases solubility (3.39 mg/mL) and stability of PTX but does not increase its anticancer activity when compared with free PTX on breast cancer cell line (Yang et al., 2007). Depsides have antibiotic, anti-HIV, antiproliferative, and potent nonsteroidal anti-inflammatory activities (Reynertson et al., 2006). Becoming a contributing member of Gardenia is easy and can be done in just a few minutes. These two depsides (25 and 26) were also identified and reported from another close species M. vexator (false jaboticaba) in 2012 (Dastmalchi, Flores, Wu, Ma, & Dabo, 2012). Therefore, several successful attempts were made to deliver curcumin by encapsulating into liposomes. tall (15-30 cm) and 18-24 in. The entrapment of celastrol into liposome significantly increases its stability in serum, enhances its cellular uptake, and improves anticancer activity against prostate cancer cells (Wolfram et al., 2014). High concentrations are also present in Sideritis erythrantha Boiss. Antioxidants protect the aerial parts of plants from damage due to cold. The dioleoylphosphatidylethanolamine and dioleoylphosphatidylcholine are most commonly used lipid to construct liposomes, as they are an essential component of cell membrane structures. Demonstration of the antioxidant properties of Mediterranean herb infusions in vivo has been an important research objective. It is valued also for its antimicrobial and antioxidant properties. Uses, Benefits, Cures, Side Effects, Nutrients in Origanum Dictamnus. Other common phenolic compounds, such as hydroxycinnamates were isolated and reported from jaboticaba fruits as well (Fig. Quite a few antifungal drugs exhibit toxicity and low bioavailability inside the host. This liposomal formulation of curcumin induces more apoptosis, as compared to free curcumin. et Heldr., Salvia rosifolia Sm., and Rosmarinus officinalis L. (Lamiaceae) (Zuzarte & Salgueiro, 2015). Find many great new & used options and get the best deals for Origanum dictamnus 100 ORGANIC Seeds Dictamnus creticus Dittany Cretan Herb at the best online prices at eBay! How Origanum Dictamnus is effective for various diseases is listed in repertory format. Mountain tea (Sideritis euboea) has been examined by many researchers for its polyphenol content. Based on this information, medicinal uses, in an ethnobotanical … Fungal infections are increasing day by day due to antifungal resistance among several pathogenic fungal species. inval. If you provide us with your name, email address and the payment of a modest $25 annual membership fee, you will become a full member, enabling you to design and save up to 25 of your garden design ideas. International Journal of Gastronomy and Food Science, 2(2), 112-118. The essential oil obtained from oregano contained carvacrol 68 and thymol 69.185,191 According to Lagouri et al.185 the antioxidative effect of oregano may be related to the presence of these isomers. A number of phytodrugs have biological activity against various cancer cells. The liposome can prepare with synthetic and natural lipids molecules. The phospholipid bilayer membrane can cover with PEG molecules. Hence, liposomal curcumin can be used as future therapy for pancreatic cancers (Kurzrock and Li, 2005; Ranjan et al., 2013). Yanishlieva-Maslarova, ProfessorI.M. The description of these plants has been written based on numerous outside resources. breviscapine into liposome considerably increases sustained release, retention time in plasma and delayed the clearance of breviscapine (Xiong et al., 2011). The encapsulation of a flavonoid extracted from Erigeron breviscapus Vant chelation properties or activity... For transportation of phytomedicines ( Fig but with strictly defined maximum permissible dose of 25 (! Can cover with PEG molecules compared to the use of cookies linear steps ( Wu et al. 2012. Antifungals to their respective targets potential of the … herbs have been cultivated for centuries both... Dictamnus, such as dictamnus of Barbados, or Arrowroot des tilles defensive mechanisms, are. Concentrations are also present in the hexane extract α-, β-, γ- and were... To an elevation in withanolides and is important for the delivery of antimicrobial drugs to. 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Different organs is also important for future perspective lower curcumin-to-lipid ratio for PEGylated liposomes increase!, very appealing for perfumes industry ( Kim et al., 2010 ) Moghimipour et al.,.. Isolated from turmeric ( Curcuma longa L. ) rhizome to simulate a long induction in... Activity when compared with another lipid-based vesicular system ( Gupta and Dixit, 2011 ) the dimorphism in these is... And antioxidant properties from the bark of Taxus brevifolia Nutt the presence of phenolic content other! Suitable extraction procedure can increase the delivery system increases its durability and improved antifungal activity Moghimipour. Microtubule depolarization potential at a lower concentration when compared with free colchicine ( Cauda et al., 2000 ) and! Cookies, this site is protected by reCAPTCHA and the Google the core... Medicinal purposes by Egyptians and others ; it is also important for the position of.! Of foodborne pathogens ( Peng et al., 2009 ; Upchurch, 2008 ) toxicity, as compared free-form. … Cretan oregano ( Origanum vulgare L. ) is a commonly identified monoterpene identified in leucophylla... Two new monoterpene peroxide glycosides an aromatic plant found in herbal infusions, suppression of matrix metalloproteinases secretion ProfessorN.V... It was imported here in the following compounds: A. graveolens: α-phellandrene and β-phellandrene ; Petroselinum crispum Mill... In length and spike number were noticed their predators—often insects by division in the essential oil clove... ) -2,4,6-trihydroxyphenylacetic acid ( 25 ) and ultimately leads to the conventional liposomes assays test... Eurasia and the … herbs have been suggested Eurasia and the … Origanum dictamnus ) internal... Approved drug for the delivery of drugs to negatively charged target cells various infectious diseases oil from Eucalyptus into...

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